Finally, a survival analysis was carried out, comparing patients with vitamin D???10 ng/mL and those with vitamin D?<?10 ng/mL. Patients with severe vitamin D deficiency (n?=?10) had a median RICU stay of 8 days (IQ25 6, IQ75 11.25), while the remaining 32 patients had a median stay of 12.5 days (IQ 25 8, IQ75 20.5). Indeed, patients with severe vitamin D deficiency tend to have a rapid unfavorable clinical evolution, that results in 20% of cases with death (patients with vitamin D???10 ng/dL die in 3.1% of cases) and in 20% with transfer to ICU (patients with vitamin D???10 ng/dL are transferred to ICU in 12.5% of cases). After 10 days, patients with severe vitamin D deficiency had a 50% probability of dying, while those with vitamin D???10 ng/mL had a 5% mortality risk (p?=?0.019) (Fig. 1).
Vitamin D deficiency as a predictor of poor prognosis in patients with acute respiratory failure due to COVID-19